Drug Discovery

Drug discovery is a process, which aims at identifying a compound therapeutically useful in treating and curing a disease. Typically a drug discovery effort addresses a biological target that has been shown to play a role in the development of the disease or starts from a molecule with interesting biological activities.
The process of drug discovery involves the identification of candidates, synthesis, characterization, screening, and assays for therapeutic efficacy. Once a compound has shown its value in these tests, it will begin the process of drug development prior to clinical trials. Drug discovery and development is an expensive process due to the high costs of R&D and human clinical tests. The average total cost per drug development varies from US$ 897 million to US$ 1.9 billion. The typical development time is 10-15 years. In the past most drugs have been discovered either by identifying the active ingredient from traditional remedies or by serendipitous discovery. At present a new approach is being tried to understand how disease and infection are controlled at the molecular and physiological level and to target specific entities based on this knowledge.

The worldwide market for medication revelation advancements and items came to $38.4 billion in 2011. It has extended to $41.4 billion in 2012 and to $79.0 billion by 2017, a compound yearly development rate (CAGR) of 13.8% somewhere around 2012 and 2017.

 

  • Steps in Modern Drug Discovery
  • Lead Discovery Methods
  • Advanced Technologies involved in Drug Discovery

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